Editorial insights on photochemistry and photoredox catalysis

Curated research highlights for scientists exploring light-driven chemistry

Blue Light-Mediated Decarboxylative Coupling Transforms Carboxylic Acid Feedstocks
Synthesis

Blue Light-Mediated Decarboxylative Coupling Transforms Carboxylic Acid Feedstocks

A simple photocatalytic system enables direct decarboxylative coupling of abundant carboxylic acids with alkenes, providing atom-economical routes to functionalized molecules.

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Photoredox-Mediated Peptide Stapling Enables Selective Protein-Protein Interaction Inhibitors
Biology

Photoredox-Mediated Peptide Stapling Enables Selective Protein-Protein Interaction Inhibitors

A novel photoredox approach for installing hydrocarbon staples into peptides yields cell-permeable inhibitors with enhanced proteolytic stability and binding affinity.

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Asymmetric Photoredox Organocatalysis Unlocks Chiral Building Blocks
Synthesis

Asymmetric Photoredox Organocatalysis Unlocks Chiral Building Blocks

Combining chiral organocatalysts with photoredox catalysis achieves highly enantioselective radical additions, providing new routes to valuable chiral building blocks for pharmaceutical synthesis.

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Engineered Metal-Organic Frameworks Achieve Record CO₂ Reduction Efficiency
Materials

Engineered Metal-Organic Frameworks Achieve Record CO₂ Reduction Efficiency

A newly designed MOF photocatalyst demonstrates unprecedented quantum efficiency for visible-light-driven CO₂ reduction to formate, surpassing benchmark systems by nearly 300%.

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Crystalline Covalent Organic Frameworks Enable Efficient Photocatalytic Water Splitting
Materials

Crystalline Covalent Organic Frameworks Enable Efficient Photocatalytic Water Splitting

A precisely designed COF structure integrates donor-acceptor motifs and platinum cocatalysts to achieve benchmark hydrogen evolution rates under visible light without sacrificial agents.

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Dual Nickel-Photoredox Catalysis Enables Unprecedented C-H Functionalization
Photoredox

Dual Nickel-Photoredox Catalysis Enables Unprecedented C-H Functionalization

Researchers demonstrate a new dual catalytic system combining nickel and photoredox catalysis to achieve direct C-H bond functionalization under mild conditions, opening pathways for late-stage drug modification.

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